About Center for System Genomics
The Center for Systems Genomics (CSG) was established in January of 2012 to bring together faculty interested in Systems Genomics at Pennsylvania State University. The research mission of the CSG is to integrate variation in DNA sequence, structural variation, gene expression, metabolomic, epigenetic, and proteomic data along with the environment to explore and dissect the genomic architecture of complex traits, leading to improved understanding of the biology and etiology of disease. Other CSG activities include a weekly genomics seminar series, a weekly journal club, and an annual retreat.
Khoisan hunter-gatherers have been the largest population throughout the majority of modern human demographic history.
Kim HL, Ratan A, Perry GH, Montenegro A, Miller W, & Schuster SC, Nature Communications 5:5692.
Natural selection for the Duffy-null allele in the recently admixed people of Madagascar.
Hodgson JA, Pickrell JK, Pearson LN, Quillen EE, Prista A, Rocha J, Soodyall H, Shriver MD, & Perry GH, Proceedings of the Royal Society B 281: 2014930.
Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers.
Perry GH, Foll M, Grenier JC, Patin E, Nedelec Y, Pacis A, Barakatt M, Gravel S, Zhou X, Nsobya S, Excoffier L, Quintana-Murci L, Dominy NJ, & Barreiro LB, Proceedings of the National Academy of Sciences, USA 111:E3596-603.